Sandbox Reserved 769: Difference between revisions
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[[Image:Tryptophan Synthase Dimer 3.png|250px|left|thumb| ]] | [[Image:Tryptophan Synthase Dimer 3.png|250px|left|thumb| ]] | ||
= | =Tryptophan Synthase= | ||
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β subunit reaction: The βLys87, βGlu109, and βSer377 are thought to be directly involved in the catalysis as shown.<ref name="cite7">http://tryptophan.net/Trpsynthase/Tryptophan%20Synthase.html</ref> | β subunit reaction: The βLys87, βGlu109, and βSer377 are thought to be directly involved in the catalysis as shown.<ref name="cite7">http://tryptophan.net/Trpsynthase/Tryptophan%20Synthase.html</ref> | ||
==Medical Relevance== | |||
As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target. | |||
Inhibition of tryptophan synthase in amino acid metabolism has been suggested for:<ref name="info">http://en.wikipedia.org/wiki/Tryptophan_synthase</ref> | |||
• Treatment of tuberculosis | |||
• Treatment of ocular and genital infections | |||
• Treatment of cryptosporidiosis | |||
• Herbicide use | |||
==References== | ==References== | ||
<references /> | <references /> | ||
