4nnd: Difference between revisions
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==Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites== | |||
<StructureSection load='4nnd' size='340' side='right'caption='[[4nnd]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4nnd]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NND OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NND FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.502Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnd OCA], [https://pdbe.org/4nnd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnd RCSB], [https://www.ebi.ac.uk/pdbsum/4nnd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnd ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. | |||
==See Also== | |||
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Du Y]] | |||
[[Category: Wang H]] | |||
[[Category: Yang D]] | |||
[[Category: Yang F]] | |||
Latest revision as of 08:27, 9 October 2024
Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites
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