4nuf: Difference between revisions

(6 intermediate revisions by the same user not shown)

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 4nuf is ~~ON HOLD~~

==Crystal Structure of SHP/EID1==

== Structural highlights ==

<table><tr><td colspan='2'>[[4nuf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O104:H4_str._2009EL-2071 Escherichia coli O104:H4 str. 2009EL-2071] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NUF OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4NUF FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4nuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nuf OCA], [https://pdbe.org/4nuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nuf RCSB], [https://www.ebi.ac.uk/pdbsum/4nuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nuf ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/NR0B2_MOUSE NR0B2_MOUSE] Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.<ref>PMID:8650544</ref>

~~Authors~~: ~~Zhi, X~~.~~, X.E.Z.,~~ K~~.M.,~~ Xu~~, H.E.~~

==See Also==

*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]]

~~Description~~: ~~Crystal Structure of SHP/EID1~~

== References ==

__TOC__

</StructureSection>

[[Category: Escherichia coli O104:H4 str. 2009EL-2071]]

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: He Y]]

[[Category: Kliewer SA]]

[[Category: Mangelsdorf DJ]]

[[Category: Melcher K]]

[[Category: Suino-Powell KM]]

[[Category: Xu HE]]

[[Category: Zechner C]]

[[Category: Zhi X]]

[[Category: Zhou XE]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4nuf is ON HOLD
+==Crystal Structure of SHP/EID1==
+<StructureSection load='4nuf' size='340' side='right'caption='[[4nuf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4nuf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O104:H4_str._2009EL-2071 Escherichia coli O104:H4 str. 2009EL-2071] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NUF FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nuf OCA], [https://pdbe.org/4nuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nuf RCSB], [https://www.ebi.ac.uk/pdbsum/4nuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nuf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/NR0B2_MOUSE NR0B2_MOUSE] Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.<ref>PMID:8650544</ref>
-Authors: Zhi, X., X.E.Z., K.M., Xu, H.E.
+==See Also==
+*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]]
-Description: Crystal Structure of SHP/EID1
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli O104:H4 str. 2009EL-2071]]
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: He Y]]
+[[Category: Kliewer SA]]
+[[Category: Mangelsdorf DJ]]
+[[Category: Melcher K]]
+[[Category: Suino-Powell KM]]
+[[Category: Xu HE]]
+[[Category: Zechner C]]
+[[Category: Zhi X]]
+[[Category: Zhou XE]]