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{{STRUCTURE_4nsn|  PDB=4nsn  |  SCENE=  }}
===Crystal structure of purine nucleoside phosphorylase from Porphyromonas gingivalis ATCC 33277, NYSGRC Target 030972, orthorhombic symmetry===


==Function==
==Crystal structure of purine nucleoside phosphorylase from Porphyromonas gingivalis ATCC 33277, NYSGRC Target 030972, orthorhombic symmetry==
[[http://www.uniprot.org/uniprot/B2RKN6_PORG3 B2RKN6_PORG3]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).[PIRNR:PIRNR000477]  
<StructureSection load='4nsn' size='340' side='right'caption='[[4nsn]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4nsn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_ATCC_33277 Porphyromonas gingivalis ATCC 33277]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NSN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nsn OCA], [https://pdbe.org/4nsn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nsn RCSB], [https://www.ebi.ac.uk/pdbsum/4nsn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nsn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B2RKN6_PORG3 B2RKN6_PORG3] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).[PIRNR:PIRNR000477]


==About this Structure==
==See Also==
[[4nsn]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NSN OCA].
*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
[[Category: Purine-nucleoside phosphorylase]]
__TOC__
[[Category: Almo, S C.]]
</StructureSection>
[[Category: Bhosle, R.]]
[[Category: Large Structures]]
[[Category: Bonanno, J B.]]
[[Category: Porphyromonas gingivalis ATCC 33277]]
[[Category: Celikgil, A.]]
[[Category: Almo SC]]
[[Category: Chamala, S.]]
[[Category: Bhosle R]]
[[Category: Chan, M K.]]
[[Category: Bonanno JB]]
[[Category: Evans, B.]]
[[Category: Celikgil A]]
[[Category: Fiser, A.]]
[[Category: Chamala S]]
[[Category: Garforth, S.]]
[[Category: Chan MK]]
[[Category: Gizzi, A.]]
[[Category: Evans B]]
[[Category: Hillerich, B.]]
[[Category: Fiser A]]
[[Category: Kar, A.]]
[[Category: Garforth S]]
[[Category: Lafluer, J.]]
[[Category: Gizzi A]]
[[Category: Lim, S.]]
[[Category: Hillerich B]]
[[Category: Love, J.]]
[[Category: Kar A]]
[[Category: Malashkevich, V N.]]
[[Category: Lafluer J]]
[[Category: Matikainen, B.]]
[[Category: Lim S]]
[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
[[Category: Love J]]
[[Category: Patel, H.]]
[[Category: Malashkevich VN]]
[[Category: Seidel, R.]]
[[Category: Matikainen B]]
[[Category: Toro, R.]]
[[Category: Patel H]]
[[Category: Villegas, G.]]
[[Category: Seidel R]]
[[Category: New york structural genomics research consortium]]
[[Category: Toro R]]
[[Category: Nysgrc]]
[[Category: Villegas G]]
[[Category: Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
[[Category: Transferase]]

Latest revision as of 17:03, 20 September 2023

Crystal structure of purine nucleoside phosphorylase from Porphyromonas gingivalis ATCC 33277, NYSGRC Target 030972, orthorhombic symmetry

4nsn, resolution 1.60Å

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