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{{STRUCTURE_4lng|  PDB=4lng  |  SCENE=  }}
===Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib===
{{ABSTRACT_PUBMED_24347326}}


==About this Structure==
==Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib==
[[4lng]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNG OCA].  
<StructureSection load='4lng' size='340' side='right'caption='[[4lng]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4lng]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LNG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.905&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=JAN:6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE'>JAN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lng OCA], [https://pdbe.org/4lng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lng RCSB], [https://www.ebi.ac.uk/pdbsum/4lng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lng ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4WP27_ASPFU Q4WP27_ASPFU]


==Reference==
==See Also==
<ref group="xtra">PMID:024347326</ref><references group="xtra"/><references/>
*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
[[Category: Protein farnesyltransferase]]
__TOC__
[[Category: Beese, L S.]]
</StructureSection>
[[Category: Hast, M A.]]
[[Category: Aspergillus fumigatus Af293]]
[[Category: Mabanglo, M F.]]
[[Category: Large Structures]]
[[Category: Farnesylation]]
[[Category: Beese LS]]
[[Category: Farnesyltransferase]]
[[Category: Hast MA]]
[[Category: Isoprenoid and caax-containing protein and peptide substrate]]
[[Category: Mabanglo MF]]
[[Category: Prenylation]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4lng"