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[[Image:2ysi.jpg|left|200px]]<br /><applet load="2ysi" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ysi" />
'''Solution structure of the first WW domain from the mouse transcription elongation regulator 1, transcription factor CA150'''<br />


==About this Structure==
==Solution structure of the first WW domain from the mouse transcription elongation regulator 1, transcription factor CA150==
2YSI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YSI OCA].  
<StructureSection load='2ysi' size='340' side='right'caption='[[2ysi]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ysi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YSI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ysi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ysi OCA], [https://pdbe.org/2ysi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ysi RCSB], [https://www.ebi.ac.uk/pdbsum/2ysi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ysi ProSAT], [https://www.topsan.org/Proteins/RSGI/2ysi TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TCRG1_MOUSE TCRG1_MOUSE] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/2ysi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ysi ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Harada T]]
[[Category: Harada, T.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Koshiba S]]
[[Category: Koshiba, S.]]
[[Category: Li H]]
[[Category: Li, H.]]
[[Category: Ohnishi S]]
[[Category: Ohnishi, S.]]
[[Category: Watanabe S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Watanabe, S.]]
[[Category: Yokoyama, S.]]
[[Category: ca150]]
[[Category: fbp28]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nmr]]
[[Category: nppsfa]]
[[Category: protein binding]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transcription elongation regulator 1]]
[[Category: ww domain]]
 
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Retrieved from "https://proteopedia.org/2ysi"