2yxy: Difference between revisions

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[[Image:2yxy.gif|left|200px]]<br /><applet load="2yxy" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2yxy, resolution 2.20&Aring;" />
'''Crystarl structure of Hypothetical conserved protein, GK0453'''<br />


==About this Structure==
==Crystarl structure of Hypothetical conserved protein, GK0453==
2YXY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXY OCA].  
<StructureSection load='2yxy' size='340' side='right'caption='[[2yxy]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
[[Category: Geobacillus kaustophilus]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2yxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_kaustophilus_HTA426 Geobacillus kaustophilus HTA426]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXY FirstGlance]. <br>
[[Category: Bessho, Y.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Nakamu, Y.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxy OCA], [https://pdbe.org/2yxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxy RCSB], [https://www.ebi.ac.uk/pdbsum/2yxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxy ProSAT], [https://www.topsan.org/Proteins/RSGI/2yxy TOPSAN]</span></td></tr>
[[Category: Padmanabhan, B.]]
</table>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
== Function ==
[[Category: Yokoyama, S.]]
[https://www.uniprot.org/uniprot/Q5L2U2_GEOKA Q5L2U2_GEOKA]  
[[Category: alpha and beta proteins (a+b) class]]
== Evolutionary Conservation ==
[[Category: gk0453]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: national project on protein structural and functional analyses]]
Check<jmol>
[[Category: nppsfa]]
  <jmolCheckbox>
[[Category: riken structural genomics/proteomics initiative]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxy_consurf.spt"</scriptWhenChecked>
[[Category: rsgi]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: structural genomics]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: unknown function]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yxy ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The crystal structure of a conserved hypothetical protein, GK0453, from Geobacillus kaustophilus has been determined to 2.2 A resolution. The crystal belonged to space group P43212, with unit-cell parameters a = b = 75.69, c = 64.18 A. The structure was determined by the molecular-replacement method and was refined to a final R factor of 22.6% (Rfree = 26.3%). Based on structural homology, the GK0453 protein possesses two independent binding sites and hence it may simultaneously interact with two proteins or with a protein and a nucleic acid.


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:58:40 2008''
Structure of the hypothetical DUF1811-family protein GK0453 from Geobacillus kaustophilus HTA426.,Padmanabhan B, Nakamura Y, Antonyuk SV, Strange RW, Hasnain SS, Yokoyama S, Bessho Y Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):342-5. doi:, 10.1107/S1744309113003369. Epub 2013 Mar 28. PMID:23545635<ref>PMID:23545635</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2yxy" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Geobacillus kaustophilus HTA426]]
[[Category: Large Structures]]
[[Category: Bessho Y]]
[[Category: Nakamu Y]]
[[Category: Padmanabhan B]]
[[Category: Yokoyama S]]
Retrieved from "https://proteopedia.org/2yxy"