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[[Image:2yzk.jpg|left|200px]]<br /><applet load="2yzk" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2yzk, resolution 1.80&Aring;" />
'''Crystal structure of orotate phosphoribosyltransferase from Aeropyrum pernix'''<br />


==About this Structure==
==Crystal structure of orotate phosphoribosyltransferase from Aeropyrum pernix==
2YZK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZK OCA].  
<StructureSection load='2yzk' size='340' side='right'caption='[[2yzk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2yzk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzk OCA], [https://pdbe.org/2yzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yzk RCSB], [https://www.ebi.ac.uk/pdbsum/2yzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzk ProSAT], [https://www.topsan.org/Proteins/RSGI/2yzk TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yzk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yzk ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Baba S]]
[[Category: Baba, S.]]
[[Category: Kanagawa M]]
[[Category: Kanagawa, M.]]
[[Category: Kawai G]]
[[Category: Kawai, G.]]
[[Category: Kuramitsu S]]
[[Category: Kuramitsu, S.]]
[[Category: Sampei G]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Sampei, G.]]
[[Category: Yokoyama, S.]]
[[Category: PO4]]
[[Category: glycosyltransferase]]
[[Category: magnesium]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: pyrimidine biosynthesis]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rossmann fold]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:58:55 2008''

Latest revision as of 01:32, 21 November 2024

Crystal structure of orotate phosphoribosyltransferase from Aeropyrum pernix

2yzk, resolution 1.80Å

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