2z1a: Difference between revisions

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[[Image:2z1a.jpg|left|200px]]<br /><applet load="2z1a" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2z1a, resolution 1.75&Aring;" />
'''Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8'''<br />


==About this Structure==
==Crystal structure of 5'-nucleotidase precursor from Thermus thermophilus HB8==
2Z1A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=THM:'>THM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1A OCA].  
<StructureSection load='2z1a' size='340' side='right'caption='[[2z1a]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
[[Category: 5'-nucleotidase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2z1a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z1A FirstGlance]. <br>
[[Category: Thermus thermophilus]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
[[Category: Kishishita, S.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Kuramitsu, S.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z1a OCA], [https://pdbe.org/2z1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z1a RCSB], [https://www.ebi.ac.uk/pdbsum/2z1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z1a ProSAT], [https://www.topsan.org/Proteins/RSGI/2z1a TOPSAN]</span></td></tr>
[[Category: Nakagawa, N.]]
</table>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
== Function ==
[[Category: Yokoyama, S.]]
[https://www.uniprot.org/uniprot/Q5SIP1_THET8 Q5SIP1_THET8]  
[[Category: PO4]]
== Evolutionary Conservation ==
[[Category: THM]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: ZN]]
Check<jmol>
[[Category: hydrolase]]
  <jmolCheckbox>
[[Category: metal-binding]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z1a_consurf.spt"</scriptWhenChecked>
[[Category: national project on protein structural and functional analyses]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: nppsfa]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: nucleotidase]]
  </jmolCheckbox>
[[Category: nucleotide-binding]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z1a ConSurf].
[[Category: riken structural genomics/proteomics initiative]]
<div style="clear:both"></div>
[[Category: rsgi]]
__TOC__
[[Category: structural genomics]]
</StructureSection>
 
[[Category: Large Structures]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:59:18 2008''
[[Category: Thermus thermophilus HB8]]
[[Category: Kishishita S]]
[[Category: Kuramitsu S]]
[[Category: Nakagawa N]]
[[Category: Yokoyama S]]