4o25: Difference between revisions

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'''Unreleased structure'''


The entry 4o25 is ON HOLD  until Paper Publication
==Structure of Wild Type Mus musculus Rheb bound to GTP==
<StructureSection load='4o25' size='340' side='right'caption='[[4o25]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4o25]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O25 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o25 OCA], [https://pdbe.org/4o25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o25 RCSB], [https://www.ebi.ac.uk/pdbsum/4o25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o25 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RHEB_MOUSE RHEB_MOUSE] Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity (By similarity).


Authors: Mazhab-Jafari, M.T., Marshall, C.B., Ho, J., Ishiyama, N., Stambolic, V., Ikura, M.
==See Also==
 
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
Description: Structure of Wild Type Mus musculus Rheb bound to GTP
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Ho J]]
[[Category: Ikura M]]
[[Category: Ishiyama N]]
[[Category: Marshall CB]]
[[Category: Mazhab-Jafari MT]]
[[Category: Stambolic V]]
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