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{{STRUCTURE_4hmx|  PDB=4hmx  |  SCENE=  }}
===Crystal structure of PhzG from Burkholderia lata 383 in complex with tetrahydrophenazine-1-carboxylic acid===
{{ABSTRACT_PUBMED_23897464}}


==About this Structure==
==Crystal structure of PhzG from Burkholderia lata 383 in complex with tetrahydrophenazine-1-carboxylic acid==
[[4hmx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HMX OCA].  
<StructureSection load='4hmx' size='340' side='right'caption='[[4hmx]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hmx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_lata Burkholderia lata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HMX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=WUB:(1R,10AS)-1,2,10,10A-TETRAHYDROPHENAZINE-1-CARBOXYLIC+ACID'>WUB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hmx OCA], [https://pdbe.org/4hmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hmx RCSB], [https://www.ebi.ac.uk/pdbsum/4hmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hmx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHZG_BURL3 PHZG_BURL3] Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control (PubMed:23897464). Catalyzes several oxidations in the terminal steps of core phenazine biosynthesis. It oxidizes both hexahydrophenazine-1,6-dicarboxylic acid (HHPDC) and tetrahydrophenazine-1-carboxylic acid (THPCA) and thereby contributes to the generation of both phenazine-1,6-dicarboxylic acid (PDC) and phenazine-1-carboxylic acid (PCA). It synthesizes phenazines in their reduced form, which are the likely end products in vivo (PubMed:23897464).<ref>PMID:23897464</ref>


==Reference==
==See Also==
<ref group="xtra">PMID:023897464</ref><references group="xtra"/><references/>
*[[Pyridoxine 5'-phosphate oxidase|Pyridoxine 5'-phosphate oxidase]]
[[Category: Pyridoxal 5'-phosphate synthase]]
== References ==
[[Category: Ahuja, E G.]]
<references/>
[[Category: Blankenfeldt, W.]]
__TOC__
[[Category: Xu, N N.]]
</StructureSection>
[[Category: Apo structure]]
[[Category: Burkholderia lata]]
[[Category: Oxidoreductase]]
[[Category: Large Structures]]
[[Category: Ahuja EG]]
[[Category: Blankenfeldt W]]
[[Category: Xu NN]]
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