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{{STRUCTURE_4j1t|  PDB=4j1t  |  SCENE=  }}
===Crystal structure of Thermus thermophilus transhydrogenase heterotrimeric complex of the Alpha1 subunit dimer with the NADP binding domain (domain III) of the Beta subunit in P2(1)===


==Function==
==Crystal structure of Thermus thermophilus transhydrogenase heterotrimeric complex of the Alpha1 subunit dimer with the NADP binding domain (domain III) of the Beta subunit in P2(1)==
[[http://www.uniprot.org/uniprot/Q72GS0_THET2 Q72GS0_THET2]] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity).[PIRNR:PIRNR000204]  
<StructureSection load='4j1t' size='340' side='right'caption='[[4j1t]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4j1t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J1T FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j1t OCA], [https://pdbe.org/4j1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j1t RCSB], [https://www.ebi.ac.uk/pdbsum/4j1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j1t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q72GR8_THET2 Q72GR8_THET2]  


==About this Structure==
==See Also==
[[4j1t]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1T OCA].
*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]]
[[Category: Briccio, L A.Schurig.]]
__TOC__
[[Category: Gennis, R B.]]
</StructureSection>
[[Category: Leung, J.]]
[[Category: Large Structures]]
[[Category: Stout, C D.]]
[[Category: Thermus thermophilus HB27]]
[[Category: Yamaguchi, M.]]
[[Category: Gennis RB]]
[[Category: Complex of alpha1 subunit dimer with domain iii of beta subunit]]
[[Category: Leung J]]
[[Category: Domain iii binds to alpha1]]
[[Category: Schurig Briccio LA]]
[[Category: Nad bound to alpha1]]
[[Category: Stout CD]]
[[Category: Nadp bound to domain iii]]
[[Category: Yamaguchi M]]
[[Category: Oxidoreductase]]
[[Category: Soluble components of nicotinamide nucleotide transhydrogenase]]
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