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{{STRUCTURE_4k51|  PDB=4k51  |  SCENE=  }}
===Crystal Structure of the PCI domain of eIF3a===
{{ABSTRACT_PUBMED_24423867}}


==Function==
==Crystal Structure of the PCI domain of eIF3a==
[[http://www.uniprot.org/uniprot/EIF3A_YEAST EIF3A_YEAST]] Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.<ref>PMID:9694884</ref> <ref>PMID:11387228</ref> <ref>PMID:12651896</ref> <ref>PMID:18765792</ref>
<StructureSection load='4k51' size='340' side='right'caption='[[4k51]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4k51]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K51 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K51 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k51 OCA], [https://pdbe.org/4k51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k51 RCSB], [https://www.ebi.ac.uk/pdbsum/4k51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k51 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EIF3A_YEAST EIF3A_YEAST] Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.<ref>PMID:9694884</ref> <ref>PMID:11387228</ref> <ref>PMID:12651896</ref> <ref>PMID:18765792</ref>  


==About this Structure==
==See Also==
[[4k51]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K51 OCA].
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:024423867</ref><references group="xtra"/><references/>
__TOC__
[[Category: Ficner, R.]]
</StructureSection>
[[Category: Khoshnevis, S.]]
[[Category: Large Structures]]
[[Category: Neumann, P.]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Biosynthetic protein]]
[[Category: Ficner R]]
[[Category: Eif3]]
[[Category: Khoshnevis S]]
[[Category: Pci domain]]
[[Category: Neumann P]]
[[Category: Translation initiation]]
Retrieved from "https://proteopedia.org/4k51"