4gbe: Difference between revisions
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==Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with SAH== | |||
<StructureSection load='4gbe' size='340' side='right'caption='[[4gbe]], [[Resolution|resolution]] 2.66Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4gbe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GBE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.66Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gbe OCA], [https://pdbe.org/4gbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gbe RCSB], [https://www.ebi.ac.uk/pdbsum/4gbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gbe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DMA_ECOLI DMA_ECOLI] Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication. | |||
==See Also== | |||
*[[DNA adenine methylase|DNA adenine methylase]] | |||
*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Harmer JE]] | |||
[[Category: Roach PL]] | |||
Latest revision as of 11:27, 1 March 2024
Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with SAH
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