4ork: Difference between revisions

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'''Unreleased structure'''


The entry 4ork is ON HOLD
==Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia==
 
<StructureSection load='4ork' size='340' side='right'caption='[[4ork]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
Authors: Smith, C.A., Toth, M., Bhattacharya, M., Frase, H., Vakulenko, S.B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4ork]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ORK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ORK FirstGlance]. <br>
Description:
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ork FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ork OCA], [https://pdbe.org/4ork PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ork RCSB], [https://www.ebi.ac.uk/pdbsum/4ork PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ork ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AACA_STAAU AACA_STAAU] Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Bhattacharya M]]
[[Category: Frase H]]
[[Category: Smith CA]]
[[Category: Toth M]]
[[Category: Vakulenko SB]]
Retrieved from "https://proteopedia.org/4ork"