4p0c: Difference between revisions
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New page: '''Unreleased structure''' The entry 4p0c is ON HOLD Authors: Holcomb, Joshua, Jiang, Yuanyuan, Lu, Guorong, Trescott, Laura, Brunzelle, Joseph, Sirinupong, Nualpun, Li, Chunying, Naren... |
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==Crystal Structure of NHERF2 PDZ1 Domain in Complex with LPA2== | |||
<StructureSection load='4p0c' size='340' side='right'caption='[[4p0c]], [[Resolution|resolution]] 1.34Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4p0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P0C FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.339Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p0c OCA], [https://pdbe.org/4p0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p0c RCSB], [https://www.ebi.ac.uk/pdbsum/4p0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p0c ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NHRF2_HUMAN NHRF2_HUMAN] Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.<ref>PMID:9096337</ref> <ref>PMID:10455146</ref> | |||
==See Also== | |||
*[[Lysophosphatidic acid receptor|Lysophosphatidic acid receptor]] | |||
*[[Sandbox Reserved 1789|Sandbox Reserved 1789]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Brunzelle J]] | |||
[[Category: Holcomb J]] | |||
[[Category: Jiang Y]] | |||
[[Category: Li C]] | |||
[[Category: Lu G]] | |||
[[Category: Naren A]] | |||
[[Category: Sirinupong N]] | |||
[[Category: Trescott L]] | |||
[[Category: Yang Z]] | |||
Latest revision as of 10:16, 27 March 2024
Crystal Structure of NHERF2 PDZ1 Domain in Complex with LPA2
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