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{{STRUCTURE_4ke2|  PDB=4ke2  |  SCENE=  }}
===Crystal structure of the hyperactive Type I antifreeze from winter flounder===
{{ABSTRACT_PUBMED_15716269}}


==About this Structure==
==Crystal structure of the hyperactive Type I antifreeze from winter flounder==
[[4ke2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KE2 OCA].  
<StructureSection load='4ke2' size='340' side='right'caption='[[4ke2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ke2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudopleuronectes_americanus Pseudopleuronectes americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KE2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ke2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ke2 OCA], [https://pdbe.org/4ke2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ke2 RCSB], [https://www.ebi.ac.uk/pdbsum/4ke2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ke2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ANPM_PSEAM ANPM_PSEAM] Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point by about 1.1 degrees at a concentration of 0.1 mg/ml, and by about 1.5 degrees at a concentration of 0.2 mg/ml. Binds to nascent ice crystals and prevents further growth.<ref>PMID:15141201</ref> <ref>PMID:15716269</ref> <ref>PMID:18225917</ref> <ref>PMID:24531972</ref>


==Reference==
==See Also==
<ref group="xtra">PMID:015716269</ref><references group="xtra"/><references/>
*[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]]
[[Category: Allingham, J S.]]
== References ==
[[Category: Campbell, R L.]]
<references/>
[[Category: Davies, P L.]]
__TOC__
[[Category: Lin, F H.]]
</StructureSection>
[[Category: Sun, T.]]
[[Category: Large Structures]]
[[Category: Antifreeze protein]]
[[Category: Pseudopleuronectes americanus]]
[[Category: Dimeric alpha-helical bundle]]
[[Category: Allingham JS]]
[[Category: Campbell RL]]
[[Category: Davies PL]]
[[Category: Lin F-H]]
[[Category: Sun T]]

Latest revision as of 12:11, 1 March 2024

Crystal structure of the hyperactive Type I antifreeze from winter flounder

4ke2, resolution 1.80Å

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