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{{STRUCTURE_4nn2|  PDB=4nn2  |  SCENE=  }}
===Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6===


==Disease==
==Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6==
[[http://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN]] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.  
<StructureSection load='4nn2' size='340' side='right'caption='[[4nn2]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4nn2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NN2 FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN]] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<ref>PMID:23229552</ref>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.472&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nn2 OCA], [https://pdbe.org/4nn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nn2 RCSB], [https://www.ebi.ac.uk/pdbsum/4nn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nn2 ProSAT]</span></td></tr>
[[4nn2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN2 OCA].
</table>
 
== Disease ==
==Reference==
[https://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.
<references group="xtra"/><references/>
== Function ==
[[Category: Li,F.]]
[https://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<ref>PMID:23229552</ref>  
[[Category: Liu, Z.]]
== References ==
[[Category: Mei,Y.]]
<references/>
[[Category: Shi,Y.]]
__TOC__
[[Category: Wu, J.]]
</StructureSection>
[[Category: Zhang, J.]]
[[Category: Homo sapiens]]
[[Category: Transcription]]
[[Category: Large Structures]]
[[Category: Zinc finger]]
[[Category: Li F]]
[[Category: Liu Z]]
[[Category: Mei Y]]
[[Category: Shi Y]]
[[Category: Wu J]]
[[Category: Zhang J]]

Latest revision as of 12:34, 1 March 2024

Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6

4nn2, resolution 1.47Å

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