426d: Difference between revisions

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[[Image:426d.gif|left|200px]]<br /><applet load="426d" size="350" color="white" frame="true" align="right" spinBox="true"
caption="426d, resolution 3.0&Aring;" />
'''THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)'''<br />


==Overview==
==THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)==
The title oligonucleotide and many related dodecamers have been extensively studied alone and as DNA-drug complexes. In practically all cases they were found to crystallize in the same space group, stabilized by interactions among the terminal guanine bases. Here we report new packing interactions (R3) in the presence of Ca2+. The oligonucleotides interact by placing their terminal guanines in the narrow groove of a neighbor molecule, an interaction which had never been found in dodecamers.
<StructureSection load='426d' size='340' side='right'caption='[[426d]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[426d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=426D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=426D FirstGlance]. <br>
426D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=426D OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=426d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=426d OCA], [https://pdbe.org/426d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=426d RCSB], [https://www.ebi.ac.uk/pdbsum/426d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=426d ProSAT]</span></td></tr>
The structure of the most studied DNA fragment changes under the influence of ions: a new packing of d(CGCGAATTCGCG)., Liu J, Malinina L, Huynh-Dinh T, Subirana JA, FEBS Lett. 1998 Nov 6;438(3):211-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9827547 9827547]
</table>
[[Category: Protein complex]]
__TOC__
[[Category: Liu, J.]]
</StructureSection>
[[Category: Malinina, L.]]
[[Category: Large Structures]]
[[Category: Subirana, J A.]]
[[Category: Liu J]]
[[Category: CA]]
[[Category: Malinina L]]
[[Category: double helix]]
[[Category: Subirana JA]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:12:13 2008''

Latest revision as of 10:38, 1 March 2024

THE STRUCTURE OF MOST STUDIED DNA FRAGMENT CHANGES UNDER THE INFLUENCE OF IONS: A NEW PACKING OF D(CGCGAATTCGCG)

426d, resolution 3.00Å

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