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{{STRUCTURE_4duq|  PDB=4duq  |  SCENE=  }}
===The Structure of Ca2+-loaded S100A2 at 1.3A resolution===
{{ABSTRACT_PUBMED_22394450}}


==Function==
==The Structure of Ca2+-loaded S100A2 at 1.3A resolution==
[[http://www.uniprot.org/uniprot/S10A2_HUMAN S10A2_HUMAN]] May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.<ref>PMID:1372446</ref>
<StructureSection load='4duq' size='340' side='right'caption='[[4duq]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4duq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3n22 3n22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DUQ FirstGlance]. <br>
[[4duq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3n22 3n22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DUQ OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4duq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4duq OCA], [https://pdbe.org/4duq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4duq RCSB], [https://www.ebi.ac.uk/pdbsum/4duq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4duq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/S10A2_HUMAN S10A2_HUMAN] May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.<ref>PMID:1372446</ref>


==See Also==
==See Also==
*[[S100 protein|S100 protein]]
*[[S100 proteins 3D structures|S100 proteins 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:022394450</ref><references group="xtra"/><references/>
__TOC__
[[Category: Human]]
</StructureSection>
[[Category: Fritz, G.]]
[[Category: Homo sapiens]]
[[Category: Koch, M.]]
[[Category: Large Structures]]
[[Category: Calcium-binding]]
[[Category: Fritz G]]
[[Category: Ef-hand]]
[[Category: Koch M]]
[[Category: Metal binding protein]]
[[Category: Tumor supressor]]
[[Category: Zinc-binding]]
Retrieved from "https://proteopedia.org/4duq"