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{{STRUCTURE_4lnb|  PDB=4lnb  |  SCENE=  }}
===Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and ethylenediamine scaffold inhibitor 5===
{{ABSTRACT_PUBMED_24347326}}


==About this Structure==
==Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and ethylenediamine scaffold inhibitor 5==
[[4lnb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNB OCA].  
<StructureSection load='4lnb' size='340' side='right'caption='[[4lnb]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4lnb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LNB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.752&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ED5:TERT-BUTYL+4-({(2-{(4-CYANOPHENYL)[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]AMINO}ETHYL)[(2-METHYLPHENYL)SULFONYL]AMINO}METHYL)PIPERIDINE-1-CARBOXYLATE'>ED5</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lnb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lnb OCA], [https://pdbe.org/4lnb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lnb RCSB], [https://www.ebi.ac.uk/pdbsum/4lnb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lnb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4WP27_ASPFU Q4WP27_ASPFU]


==See Also==
==See Also==
*[[Farnesyltransferase|Farnesyltransferase]]
*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:024347326</ref><references group="xtra"/><references/>
[[Category: Aspergillus fumigatus Af293]]
[[Category: Protein farnesyltransferase]]
[[Category: Large Structures]]
[[Category: Beese, L S.]]
[[Category: Beese LS]]
[[Category: Hast, M A.]]
[[Category: Hast MA]]
[[Category: Mabanglo, M F.]]
[[Category: Mabanglo MF]]
[[Category: Farnesylation]]
[[Category: Isoprenoid and caax-containing protein substrate]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4lnb"