4px5: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
New page: '''Unreleased structure''' The entry 4px5 is ON HOLD until Paper Publication Authors: Jordan, S.R., Chmait, S. Description: Human GKRP bound to AMG-0696 and Sorbitol-6-phosphate
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 4px5 is ON HOLD  until Paper Publication
==Human GKRP bound to AMG-0696 and Sorbitol-6-phosphate==
<StructureSection load='4px5' size='340' side='right'caption='[[4px5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4px5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PX5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PX5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2WZ:N-[(R)-(2-AMINO-5-CHLORO-3-FLUOROPYRIDIN-4-YL){7-[4-(2-HYDROXYPROPAN-2-YL)PYRIDIN-2-YL]-1-BENZOTHIOPHEN-2-YL}METHYL]CYCLOPROPANESULFONAMIDE'>2WZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4px5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4px5 OCA], [https://pdbe.org/4px5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4px5 RCSB], [https://www.ebi.ac.uk/pdbsum/4px5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4px5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme.


Authors: Jordan, S.R., Chmait, S.
==See Also==
 
*[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]]
Description: Human GKRP bound to AMG-0696 and Sorbitol-6-phosphate
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chmait S]]
[[Category: Jordan SR]]
Retrieved from "https://proteopedia.org/4px5"