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{{STRUCTURE_4njt|  PDB=4njt  |  SCENE=  }}
===Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with darunavir===


==About this Structure==
==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with darunavir==
[[4njt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NJT OCA].  
<StructureSection load='4njt' size='340' side='right'caption='[[4njt]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
[[Category: Chang, S B.]]
== Structural highlights ==
[[Category: Das, D.]]
<table><tr><td colspan='2'>[[4njt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NJT FirstGlance]. <br>
[[Category: Garimella, H.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
[[Category: Ghosh, A K.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene></td></tr>
[[Category: Kaufman, J D.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4njt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4njt OCA], [https://pdbe.org/4njt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4njt RCSB], [https://www.ebi.ac.uk/pdbsum/4njt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4njt ProSAT]</span></td></tr>
[[Category: Mitsuya, H.]]
</table>
[[Category: Wingfield, P T.]]
== Function ==
[[Category: Yedidi, R S.]]
[https://www.uniprot.org/uniprot/Q9J006_9HIV1 Q9J006_9HIV1]
[[Category: Darunavir]]
 
[[Category: Hiv-1 protease]]
==See Also==
[[Category: Hydrolase-hydrolase inhibitor complex]]
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
[[Category: Multidrug-resistance]]
__TOC__
[[Category: Non-peptidic inhibitor]]
</StructureSection>
[[Category: Protease inhibitor]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Chang SB]]
[[Category: Das D]]
[[Category: Garimella H]]
[[Category: Ghosh AK]]
[[Category: Kaufman JD]]
[[Category: Mitsuya H]]
[[Category: Wingfield PT]]
[[Category: Yedidi RS]]
Retrieved from "https://proteopedia.org/4njt"