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{{STRUCTURE_3ote|  PDB=3ote  |  SCENE=  }}
===Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I===
{{ABSTRACT_PUBMED_21059936}}


==Function==
==Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I==
[[http://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN]] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref>
<StructureSection load='3ote' size='340' side='right'caption='[[3ote]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3ote]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTE FirstGlance]. <br>
[[3ote]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTE OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ote FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ote OCA], [https://pdbe.org/3ote PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ote RCSB], [https://www.ebi.ac.uk/pdbsum/3ote PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ote ProSAT]</span></td></tr>
==Reference==
</table>
<ref group="xtra">PMID:021059936</ref><references group="xtra"/><references/>
== Function ==
[[Category: Mycta]]
[https://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref>
[[Category: Doublie, S.]]
== References ==
[[Category: Eckenroth, B E.]]
<references/>
[[Category: Hyde, S J.]]
__TOC__
[[Category: Catalytic carboxylate]]
</StructureSection>
[[Category: Guanylyltransferase]]
[[Category: Homo sapiens]]
[[Category: Polymerase-like palm domain]]
[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Doublie S]]
[[Category: Eckenroth BE]]
[[Category: Hyde SJ]]

Latest revision as of 10:36, 21 February 2024

Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native I

3ote, resolution 2.56Å

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