3w83: Difference between revisions
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== | ==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-6-097== | ||
[[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC | <StructureSection load='3w83' size='340' side='right'caption='[[3w83]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3w83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W83 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W83:5-{2-[7-(METHOXYMETHOXY)NAPHTHALEN-2-YL]ETHYL}-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W83</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w83 OCA], [https://pdbe.org/3w83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w83 RCSB], [https://www.ebi.ac.uk/pdbsum/3w83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w83 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | |||
== | ==See Also== | ||
[[ | *[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]] | ||
[[Category: Aoki | __TOC__ | ||
[[Category: Balogun | </StructureSection> | ||
[[Category: Harada | [[Category: Large Structures]] | ||
[[Category: Hashimoto | [[Category: Trypanosoma cruzi strain CL Brener]] | ||
[[Category: Honma | [[Category: Aoki T]] | ||
[[Category: Iida | [[Category: Balogun EO]] | ||
[[Category: Inaoka | [[Category: Harada S]] | ||
[[Category: Inoue | [[Category: Hashimoto S]] | ||
[[Category: Kita | [[Category: Honma T]] | ||
[[Category: Kuranaga | [[Category: Iida M]] | ||
[[Category: Lee | [[Category: Inaoka DK]] | ||
[[Category: Matsuoka | [[Category: Inoue M]] | ||
[[Category: Nara | [[Category: Kita K]] | ||
[[Category: Sakamoto | [[Category: Kuranaga T]] | ||
[[Category: Shiba | [[Category: Lee N]] | ||
[[Category: Suzuki | [[Category: Matsuoka S]] | ||
[[Category: Tabuchi | [[Category: Nara T]] | ||
[[Category: Tanaka | [[Category: Sakamoto K]] | ||
[[Category: Shiba T]] | |||
[[Category: Suzuki S]] | |||
[[Category: Tabuchi T]] | |||
[[Category: Tanaka A]] | |||
Latest revision as of 12:57, 8 November 2023
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-6-097
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