2zc8: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: left|200px<br /><applet load="2zc8" size="350" color="white" frame="true" align="right" spinBox="true" caption="2zc8, resolution 1.95Å" /> '''Crystal structure of... |
No edit summary |
||
| (12 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==Crystal structure of N-Acylamino Acid Racemase from Thermus thermophilus HB8== | ||
<StructureSection load='2zc8' size='340' side='right'caption='[[2zc8]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[2zc8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZC8 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc8 OCA], [https://pdbe.org/2zc8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zc8 RCSB], [https://www.ebi.ac.uk/pdbsum/2zc8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc8 ProSAT]</span></td></tr> | ||
[ | </table> | ||
[[ | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NSAR_THET8 NSAR_THET8] Acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine (PubMed:24872444). Also converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444). Catalyzes both N-succinylamino acid racemization and OSB synthesis at equivalent rates (PubMed:24872444). However, NSAR activity is probably the protein's biological function, because menaquinone biosynthesis genes are missing in this species (Probable).<ref>PMID:24872444</ref> <ref>PMID:16740275</ref> | ||
[ | == Evolutionary Conservation == | ||
[[Category: | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[Category: | Check<jmol> | ||
[[Category: | <jmolCheckbox> | ||
[[Category: | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zc8_consurf.spt"</scriptWhenChecked> | ||
[[Category: | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[Category: | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zc8 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermus thermophilus HB8]] | |||
[[Category: Hayashida M]] | |||
[[Category: Hisano T]] | |||
[[Category: Kim SH]] | |||
[[Category: Miki K]] | |||
[[Category: Takeda K]] | |||
Latest revision as of 13:56, 13 March 2024
Crystal structure of N-Acylamino Acid Racemase from Thermus thermophilus HB8
| ||||||||||||
