1cdy: Difference between revisions

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{{STRUCTURE_1cdy|  PDB=1cdy  |  SCENE=  }}
===STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER===
{{ABSTRACT_PUBMED_8986758}}


==Function==
==STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER==
[[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.  
<StructureSection load='1cdy' size='340' side='right'caption='[[1cdy]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1cdy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CDY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cdy OCA], [https://pdbe.org/1cdy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cdy RCSB], [https://www.ebi.ac.uk/pdbsum/1cdy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cdy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/1cdy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cdy ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
[[1cdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDY OCA].
*[[CD4 3D structures|CD4 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008986758</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Brouillette, C G.]]
[[Category: Large Structures]]
[[Category: Chaiken, I M.]]
[[Category: Brouillette CG]]
[[Category: Hendrickson, W A.]]
[[Category: Chaiken IM]]
[[Category: Myszka, D.]]
[[Category: Hendrickson WA]]
[[Category: Sweet, R W.]]
[[Category: Myszka D]]
[[Category: Tendian, S W.]]
[[Category: Sweet RW]]
[[Category: Wu, H.]]
[[Category: Tendian SW]]
[[Category: Glycoprotein]]
[[Category: Wu H]]
[[Category: Immunoglobulin fold]]
[[Category: Lipoprotein]]
[[Category: Mhc]]
[[Category: T-cell]]
[[Category: T-cell surface glycoprotein]]
[[Category: Transmembrane]]

Latest revision as of 15:39, 13 March 2024

STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER

1cdy, resolution 2.00Å

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