3sw8: Difference between revisions

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{{STRUCTURE_3sw8|  PDB=3sw8  |  SCENE=  }}
===Strep Peptide Deformylase with a time dependent dichlorobenzamide-reverse hydroxamic acid===
{{ABSTRACT_PUBMED_21711014}}


==Function==
==Strep Peptide Deformylase with a time dependent dichlorobenzamide-reverse hydroxamic acid==
[[http://www.uniprot.org/uniprot/Q939R9_STREE Q939R9_STREE]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]  
<StructureSection load='3sw8' size='340' side='right'caption='[[3sw8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3sw8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SW8 FirstGlance]. <br>
[[3sw8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SW8 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.702&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5LI:2,3-DICHLORO-N-{2-[FORMYL(HYDROXY)AMINO]ETHYL}BENZAMIDE'>5LI</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sw8 OCA], [https://pdbe.org/3sw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sw8 RCSB], [https://www.ebi.ac.uk/pdbsum/3sw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sw8 ProSAT]</span></td></tr>
<ref group="xtra">PMID:021711014</ref><references group="xtra"/><references/>
</table>
[[Category: Peptide deformylase]]
== Function ==
[[Category: Campobasso, N.]]
[https://www.uniprot.org/uniprot/Q939R9_STREE Q939R9_STREE] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
[[Category: Smith, K J.]]
__TOC__
[[Category: Alpha-beta]]
</StructureSection>
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Large Structures]]
[[Category: Metal binding protein]]
[[Category: Streptococcus pneumoniae]]
[[Category: Peptide deformylase]]
[[Category: Campobasso N]]
[[Category: Smith KJ]]

Latest revision as of 09:57, 1 March 2024

Strep Peptide Deformylase with a time dependent dichlorobenzamide-reverse hydroxamic acid

3sw8, resolution 1.70Å

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