4k5b: Difference between revisions

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{{STRUCTURE_4k5b|  PDB=4k5b  |  SCENE=  }}
===Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W===


==Function==
==Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W==
[[http://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN]] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).  
<StructureSection load='4k5b' size='340' side='right'caption='[[4k5b]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4k5b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K5B FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5b OCA], [https://pdbe.org/4k5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k5b RCSB], [https://www.ebi.ac.uk/pdbsum/4k5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).


==About this Structure==
==See Also==
[[4k5b]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5B OCA].
*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
[[Category: Plueckthun, A.]]
__TOC__
[[Category: Sauer, E.]]
</StructureSection>
[[Category: Schilling, J.]]
[[Category: Bos taurus]]
[[Category: Schoeppe, J.]]
[[Category: Escherichia coli]]
[[Category: Anti-apoptotic bcl-2 family]]
[[Category: Large Structures]]
[[Category: Apoptosis]]
[[Category: Plueckthun A]]
[[Category: Bcl-w]]
[[Category: Sauer E]]
[[Category: Crystal structure]]
[[Category: Schilling J]]
[[Category: Darpin]]
[[Category: Schoeppe J]]
[[Category: Ligand binding-competent conformation]]
Retrieved from "https://proteopedia.org/4k5b"