1jg4: Difference between revisions
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== | ==Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with S-adenosylmethionine== | ||
[[http://www.uniprot.org/uniprot/PIMT_PYRFU PIMT_PYRFU | <StructureSection load='1jg4' size='340' side='right'caption='[[1jg4]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1jg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JG4 FirstGlance]. <br> | ||
[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jg4 OCA], [https://pdbe.org/1jg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jg4 RCSB], [https://www.ebi.ac.uk/pdbsum/1jg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jg4 ProSAT]</span></td></tr> | |||
< | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PIMT_PYRFU PIMT_PYRFU] Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/1jg4_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jg4 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus furiosus]] | [[Category: Pyrococcus furiosus]] | ||
[[Category: Boutz | [[Category: Boutz D]] | ||
[[Category: Clarke | [[Category: Clarke S]] | ||
[[Category: Griffith | [[Category: Griffith SC]] | ||
[[Category: Katz | [[Category: Katz J]] | ||
[[Category: Sawaya | [[Category: Sawaya MR]] | ||
[[Category: Thapar | [[Category: Thapar N]] | ||
[[Category: Yeates | [[Category: Yeates TO]] | ||
Latest revision as of 07:39, 7 February 2024
Crystal Structure of L-isoaspartyl (D-aspartyl) O-methyltransferase with S-adenosylmethionine
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