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{{STRUCTURE_4nb5|  PDB=4nb5  |  SCENE=  }}
===Crystal Structure of a transcriptional regulator===


==About this Structure==
==Crystal Structure of a transcriptional regulator==
[[4nb5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NB5 OCA].  
<StructureSection load='4nb5' size='340' side='right'caption='[[4nb5]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
[[Category: Radhakrishnan, A.]]
== Structural highlights ==
[[Category: Su, C C.]]
<table><tr><td colspan='2'>[[4nb5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NB5 FirstGlance]. <br>
[[Category: Yu, E W.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.641&#8491;</td></tr>
[[Category: Dna binding]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2JT:1,3-DIHYDROXYPROPAN-2-YL+OCTADECANOATE'>2JT</scene></td></tr>
[[Category: Dna binding protein]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nb5 OCA], [https://pdbe.org/4nb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nb5 RCSB], [https://www.ebi.ac.uk/pdbsum/4nb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nb5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MMPR5_MYCTU MMPR5_MYCTU] Controls the expression level of the Mmps2-MmpL2, MmpS4-MmpL4, and MmpS5-MmpL5 transport systems. Also controls its own expression. Acts by binding directly to the promoter regions.<ref>PMID:18851927</ref> <ref>PMID:24590481</ref> <ref>PMID:24737322</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Radhakrishnan A]]
[[Category: Su C-C]]
[[Category: Yu EW]]