4q7b: Difference between revisions

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'''Unreleased structure'''


The entry 4q7b is ON HOLD
==Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A==
<StructureSection load='4q7b' size='340' side='right'caption='[[4q7b]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4q7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q7B FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.19&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2YZ:[2-(BENZYLCARBAMOYL)-5-FLUOROPHENOXY]ACETIC+ACID'>2YZ</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q7b OCA], [https://pdbe.org/4q7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q7b RCSB], [https://www.ebi.ac.uk/pdbsum/4q7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q7b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.


Authors: Rechlin, C., Heine, A., Klebe, G.
==See Also==
 
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
Description: Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Heine A]]
[[Category: Klebe G]]
[[Category: Rechlin C]]
Retrieved from "https://proteopedia.org/4q7b"