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==Crystal structure of an avidin mutant==
==Crystal structure of an avidin mutant==
<StructureSection load='4bcs' size='340' side='right' caption='[[4bcs]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4bcs' size='340' side='right'caption='[[4bcs]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bcs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCS OCA]. <br>
<table><tr><td colspan='2'>[[4bcs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BCS FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1y52|1y52]], [[1y53|1y53]], [[1y55|1y55]], [[2fhl|2fhl]], [[2fhn|2fhn]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bcs OCA], [https://pdbe.org/4bcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bcs RCSB], [https://www.ebi.ac.uk/pdbsum/4bcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bcs ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bcs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bcs RCSB], [http://www.ebi.ac.uk/pdbsum/4bcs PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/AVR4_CHICK AVR4_CHICK]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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A novel chimeric avidin with increased thermal stability using DNA shuffling.,Taskinen B, Airenne TT, Janis J, Rahikainen R, Johnson MS, Kulomaa MS, Hytonen VP PLoS One. 2014 Mar 14;9(3):e92058. doi: 10.1371/journal.pone.0092058. eCollection, 2014. PMID:24632863<ref>PMID:24632863</ref>
A novel chimeric avidin with increased thermal stability using DNA shuffling.,Taskinen B, Airenne TT, Janis J, Rahikainen R, Johnson MS, Kulomaa MS, Hytonen VP PLoS One. 2014 Mar 14;9(3):e92058. doi: 10.1371/journal.pone.0092058. eCollection, 2014. PMID:24632863<ref>PMID:24632863</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4bcs" style="background-color:#fffaf0;"></div>
==See Also==
*[[Avidin 3D structures|Avidin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Gallus gallus]]
[[Category: Airenne, T T.]]
[[Category: Large Structures]]
[[Category: Hytonen, V P.]]
[[Category: Airenne TT]]
[[Category: Johnson, M S.]]
[[Category: Hytonen VP]]
[[Category: Kulomaa, M S.]]
[[Category: Johnson MS]]
[[Category: Niederhauser, B.]]
[[Category: Kulomaa MS]]
[[Category: Biotin-binding protein]]
[[Category: Niederhauser B]]
[[Category: Ligand binding]]
Retrieved from "https://proteopedia.org/4bcs"