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==High Resolution Solution NMR Structures of Oxaliplatin-DNA Adduct==
==High Resolution Solution NMR Structures of Oxaliplatin-DNA Adduct==
<StructureSection load='2k0u' size='340' side='right' caption='[[2k0u]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='2k0u' size='340' side='right'caption='[[2k0u]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k0u]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0U OCA]. <br>
<table><tr><td colspan='2'>[[2k0u]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0U FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PT:CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)'>1PT</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, models</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k0t|2k0t]], [[2k0v|2k0v]], [[2k0w|2k0w]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PT:CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II)'>1PT</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0u OCA], [https://pdbe.org/2k0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0u RCSB], [https://www.ebi.ac.uk/pdbsum/2k0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0u ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k0u RCSB], [http://www.ebi.ac.uk/pdbsum/2k0u PDBsum]</span></td></tr>
</table>
<table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links.,Bhattacharyya D, Ramachandran S, Sharma S, Pathmasiri W, King CL, Baskerville-Abraham I, Boysen G, Swenberg JA, Campbell SL, Dokholyan NV, Chaney SG PLoS One. 2011;6(8):e23582. Epub 2011 Aug 10. PMID:21853154<ref>PMID:21853154</ref>
Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links.,Bhattacharyya D, Ramachandran S, Sharma S, Pathmasiri W, King CL, Baskerville-Abraham I, Boysen G, Swenberg JA, Campbell SL, Dokholyan NV, Chaney SG PLoS One. 2011;6(8):e23582. Epub 2011 Aug 10. PMID:21853154<ref>PMID:21853154</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2k0u" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bhattacharyya, D.]]
[[Category: Large Structures]]
[[Category: Campbell, S L.]]
[[Category: Bhattacharyya D]]
[[Category: Chaney, S G.]]
[[Category: Campbell SL]]
[[Category: King, C L.]]
[[Category: Chaney SG]]
[[Category: Dna]]
[[Category: King CL]]
[[Category: Oxaliplatin-dna adduct]]
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