2lqy: Difference between revisions
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==Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.== | ==Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.== | ||
<StructureSection load='2lqy' size='340' side='right' caption='[[2lqy | <StructureSection load='2lqy' size='340' side='right'caption='[[2lqy]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lqy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQY OCA]. <br> | <table><tr><td colspan='2'>[[2lqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LQY FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqy OCA], [https://pdbe.org/2lqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lqy RCSB], [https://www.ebi.ac.uk/pdbsum/2lqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqy ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/GH_HHV11 GH_HHV11] The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.[HAMAP-Rule:MF_04033]<ref>PMID:17548810</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structure and Orientation of the gH625-644 Membrane Interacting Region of Herpes Simplex Virus Type 1 in a Membrane Mimetic System.,Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C Biochemistry. 2012 Apr 10;51(14):3121-8. Epub 2012 Mar 23. PMID:22397737<ref>PMID:22397737</ref> | Structure and Orientation of the gH625-644 Membrane Interacting Region of Herpes Simplex Virus Type 1 in a Membrane Mimetic System.,Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C Biochemistry. 2012 Apr 10;51(14):3121-8. Epub 2012 Mar 23. PMID:22397737<ref>PMID:22397737</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2lqy" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cantisani | [[Category: Human alphaherpesvirus 1]] | ||
[[Category: Falanga | [[Category: Large Structures]] | ||
[[Category: Fattorusso | [[Category: Cantisani M]] | ||
[[Category: Galdiero | [[Category: Falanga A]] | ||
[[Category: Galdiero | [[Category: Fattorusso R]] | ||
[[Category: Isernia | [[Category: Galdiero M]] | ||
[[Category: Malgieri | [[Category: Galdiero S]] | ||
[[Category: Russo | [[Category: Isernia C]] | ||
[[Category: Vitiello | [[Category: Malgieri G]] | ||
[[Category: Russo L]] | |||
[[Category: Vitiello M]] | |||
Latest revision as of 05:49, 15 May 2024
Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.
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