2vy9: Difference between revisions

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==MOLECULAR ARCHITECTURE OF THE STRESSOSOME, A SIGNAL INTEGRATION AND TRANSDUCTION HUB==
 
<StructureSection load='2vy9' size='340' side='right' caption='[[2vy9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
==Molecular architecture of the stressosome, a signal integration and transduction hub==
<StructureSection load='2vy9' size='340' side='right'caption='[[2vy9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vy9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Moorella_thermoacetica Moorella thermoacetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VY9 OCA]. <br>
<table><tr><td colspan='2'>[[2vy9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moorella_thermoacetica Moorella thermoacetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VY9 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vy9 RCSB], [http://www.ebi.ac.uk/pdbsum/2vy9 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vy9 OCA], [https://pdbe.org/2vy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vy9 RCSB], [https://www.ebi.ac.uk/pdbsum/2vy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vy9 ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q2RIF5_MOOTA Q2RIF5_MOOTA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vy/2vy9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vy/2vy9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vy9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Molecular architecture of the "stressosome," a signal integration and transduction hub.,Marles-Wright J, Grant T, Delumeau O, van Duinen G, Firbank SJ, Lewis PJ, Murray JW, Newman JA, Quin MB, Race PR, Rohou A, Tichelaar W, van Heel M, Lewis RJ Science. 2008 Oct 3;322(5898):92-6. PMID:18832644<ref>PMID:18832644</ref>
Molecular architecture of the "stressosome," a signal integration and transduction hub.,Marles-Wright J, Grant T, Delumeau O, van Duinen G, Firbank SJ, Lewis PJ, Murray JW, Newman JA, Quin MB, Race PR, Rohou A, Tichelaar W, van Heel M, Lewis RJ Science. 2008 Oct 3;322(5898):92-6. PMID:18832644<ref>PMID:18832644</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2vy9" style="background-color:#fffaf0;"></div>
==See Also==
*[[Anti-sigma factor antagonist 3D structures|Anti-sigma factor antagonist 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Moorella thermoacetica]]
[[Category: Moorella thermoacetica]]
[[Category: Delumeau, O.]]
[[Category: Delumeau O]]
[[Category: Duinen, G Van.]]
[[Category: Firbank SJ]]
[[Category: Firbank, S J.]]
[[Category: Grant T]]
[[Category: Grant, T.]]
[[Category: Lewis PJ]]
[[Category: Heel, M Van.]]
[[Category: Lewis RJ]]
[[Category: Lewis, P J.]]
[[Category: Marles-Wright J]]
[[Category: Lewis, R J.]]
[[Category: Murray JW]]
[[Category: Marles-Wright, J.]]
[[Category: Newman JA]]
[[Category: Murray, J W.]]
[[Category: Quin MB]]
[[Category: Newman, J A.]]
[[Category: Race PR]]
[[Category: Quin, M B.]]
[[Category: Rohou A]]
[[Category: Race, P R.]]
[[Category: Tichelaar W]]
[[Category: Rohou, A.]]
[[Category: Van Duinen G]]
[[Category: Tichelaar, W.]]
[[Category: Van Heel M]]
[[Category: Bacillus subtili]]
[[Category: Gene regulation]]
[[Category: Moorella thermoacetica]]
[[Category: Rsb]]
[[Category: Stas domain]]
[[Category: Stressosome]]