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==Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA==
==Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA==
<StructureSection load='2loa' size='340' side='right' caption='[[2loa]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='2loa' size='340' side='right'caption='[[2loa]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2loa]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOA OCA]. <br>
<table><tr><td colspan='2'>[[2loa]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOA FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C4Q:4-(1,4,7,10-TETRAAZACYCLODODECAN-1-YLMETHYL)QUINOLINE'>C4Q</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2lo5|2lo5]], [[2lo8|2lo8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C4Q:4-(1,4,7,10-TETRAAZACYCLODODECAN-1-YLMETHYL)QUINOLINE'>C4Q</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2loa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2loa OCA], [https://pdbe.org/2loa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2loa RCSB], [https://www.ebi.ac.uk/pdbsum/2loa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2loa ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2loa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2loa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2loa RCSB], [http://www.ebi.ac.uk/pdbsum/2loa PDBsum]</span></td></tr>
</table>
<table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.,Del Mundo IM, Siters KE, Fountain MA, Morrow JR Inorg Chem. 2012 May 7;51(9):5444-57. Epub 2012 Apr 16. PMID:22507054<ref>PMID:22507054</ref>
Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.,Del Mundo IM, Siters KE, Fountain MA, Morrow JR Inorg Chem. 2012 May 7;51(9):5444-57. Epub 2012 Apr 16. PMID:22507054<ref>PMID:22507054</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2loa" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fountain, M A.]]
[[Category: Large Structures]]
[[Category: Morrow, J R.]]
[[Category: Fountain MA]]
[[Category: Mundo, I A.del.]]
[[Category: Morrow JR]]
[[Category: Siter, K E.]]
[[Category: Siter KE]]
[[Category: Cyclen]]
[[Category: Del Mundo IA]]
[[Category: Dna]]
[[Category: Thymine bulge]]
Retrieved from "https://proteopedia.org/2loa"