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==CRYSTAL STRUCTURE OF TIP-ALPHA N34 (HP0596) FROM HELICOBACTER PYLORI AT PH8==
 
<StructureSection load='2wcr' size='340' side='right' caption='[[2wcr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
==Crystal Structure of Tip-Alpha N34 (HP0596) from Helicobacter pylori at pH8==
<StructureSection load='2wcr' size='340' side='right'caption='[[2wcr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wcr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCR OCA]. <br>
<table><tr><td colspan='2'>[[2wcr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WCR FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wcq|2wcq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcr OCA], [https://pdbe.org/2wcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wcr RCSB], [https://www.ebi.ac.uk/pdbsum/2wcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wcr ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wcr RCSB], [http://www.ebi.ac.uk/pdbsum/2wcr PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/O25318_HELPY O25318_HELPY]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structures of the tumor necrosis factor alpha inducing protein Tipalpha: a novel virulence factor from Helicobacter pylori.,Tosi T, Cioci G, Jouravleva K, Dian C, Terradot L FEBS Lett. 2009 May 19;583(10):1581-5. Epub 2009 May 4. PMID:19401200<ref>PMID:19401200</ref>
Structures of the tumor necrosis factor alpha inducing protein Tipalpha: a novel virulence factor from Helicobacter pylori.,Tosi T, Cioci G, Jouravleva K, Dian C, Terradot L FEBS Lett. 2009 May 19;583(10):1581-5. Epub 2009 May 4. PMID:19401200<ref>PMID:19401200</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2wcr" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Cioci, G.]]
[[Category: Large Structures]]
[[Category: Dian, C.]]
[[Category: Cioci G]]
[[Category: Jouravleva, K.]]
[[Category: Dian C]]
[[Category: Terradot, L.]]
[[Category: Jouravleva K]]
[[Category: Tosi, T.]]
[[Category: Terradot L]]
[[Category: Helicobacter pylori]]
[[Category: Tosi T]]
[[Category: Hp0596]]
[[Category: Immune system]]
[[Category: Tip-alpha]]

Latest revision as of 15:52, 13 December 2023

Crystal Structure of Tip-Alpha N34 (HP0596) from Helicobacter pylori at pH8

2wcr, resolution 1.70Å

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