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==Crystal structure of S. aureus MepR-DNA complex==
==Crystal structure of S. aureus MepR-DNA complex==
<StructureSection load='4lln' size='340' side='right' caption='[[4lln]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
<StructureSection load='4lln' size='340' side='right'caption='[[4lln]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lln]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLN OCA]. <br>
<table><tr><td colspan='2'>[[4lln]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLN FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lll|4lll]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.842&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lln OCA], [https://pdbe.org/4lln PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lln RCSB], [https://www.ebi.ac.uk/pdbsum/4lln PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lln ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lln OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lln RCSB], [http://www.ebi.ac.uk/pdbsum/4lln PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/Q5Y812_STAAU Q5Y812_STAAU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.,Birukou I, Seo SM, Schindler BD, Kaatz GW, Brennan RG Nucleic Acids Res. 2014 Feb;42(4):2774-88. doi: 10.1093/nar/gkt1215. Epub 2013, Nov 28. PMID:24293644<ref>PMID:24293644</ref>
Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.,Birukou I, Seo SM, Schindler BD, Kaatz GW, Brennan RG Nucleic Acids Res. 2014 Feb;42(4):2774-88. doi: 10.1093/nar/gkt1215. Epub 2013, Nov 28. PMID:24293644<ref>PMID:24293644</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4lln" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Birukou, I.]]
[[Category: Large Structures]]
[[Category: Brennan, R G.]]
[[Category: Staphylococcus aureus]]
[[Category: Mepr operator]]
[[Category: Birukou I]]
[[Category: Multidrug resistance]]
[[Category: Brennan RG]]
[[Category: Transcription repression]]
[[Category: Transcription-dna complex]]
[[Category: Winged helix-turn-helix]]