3azv: Difference between revisions

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==Crystal structure of the receptor binding domain==
==Crystal structure of the receptor binding domain==
<StructureSection load='3azv' size='340' side='right' caption='[[3azv]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='3azv' size='340' side='right'caption='[[3azv]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3azv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AZV FirstGlance]. <br>
<table><tr><td colspan='2'>[[3azv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AZV FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n7l|3n7l]], [[3azw|3azw]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3azv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3azv OCA], [https://pdbe.org/3azv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3azv RCSB], [https://www.ebi.ac.uk/pdbsum/3azv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3azv ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bont ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1491 Clostridium botulinum])</td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3azv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3azv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3azv RCSB], [http://www.ebi.ac.uk/pdbsum/3azv PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/Q9LBR1_CLOBO Q9LBR1_CLOBO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural and mutational analyses of the receptor binding domain of botulinum D/C mosaic neurotoxin: insight into the ganglioside binding mechanism.,Nuemket N, Tanaka Y, Tsukamoto K, Tsuji T, Nakamura K, Kozaki S, Yao M, Tanaka I Biochem Biophys Res Commun. 2011 Jul 29;411(2):433-9. Epub 2011 Jul 2. PMID:21749855<ref>PMID:21749855</ref>
Structural and mutational analyses of the receptor binding domain of botulinum D/C mosaic neurotoxin: insight into the ganglioside binding mechanism.,Nuemket N, Tanaka Y, Tsukamoto K, Tsuji T, Nakamura K, Kozaki S, Yao M, Tanaka I Biochem Biophys Res Commun. 2011 Jul 29;411(2):433-9. Epub 2011 Jul 2. PMID:21749855<ref>PMID:21749855</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3azv" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Kozaki, S.]]
[[Category: Large Structures]]
[[Category: Nakamura, K.]]
[[Category: Kozaki S]]
[[Category: Nuemket, N.]]
[[Category: Nakamura K]]
[[Category: Tanaka, I.]]
[[Category: Nuemket N]]
[[Category: Tanaka, Y.]]
[[Category: Tanaka I]]
[[Category: Tsuji, T.]]
[[Category: Tanaka Y]]
[[Category: Tsukamoto, K.]]
[[Category: Tsuji T]]
[[Category: Yao, M.]]
[[Category: Tsukamoto K]]
[[Category: Beta-sheet jellyroll]]
[[Category: Yao M]]
[[Category: Beta-trefoil fold]]
[[Category: Extra-cellular]]
[[Category: Ganglioside]]
[[Category: Receptor binding]]
[[Category: Toxin]]
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