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==Crystal Structure of an anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua==
==Crystal Structure of an anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua==
<StructureSection load='3a0c' size='340' side='right' caption='[[3a0c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3a0c' size='340' side='right'caption='[[3a0c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a0c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Polygonatum_cyrtonema Polygonatum cyrtonema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A0C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a0c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Polygonatum_cyrtonema Polygonatum cyrtonema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A0C FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3a0d|3a0d]], [[3a0e|3a0e]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a0c RCSB], [http://www.ebi.ac.uk/pdbsum/3a0c PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a0c OCA], [https://pdbe.org/3a0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a0c RCSB], [https://www.ebi.ac.uk/pdbsum/3a0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a0c ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8L568_9ASPA Q8L568_9ASPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/3a0c_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a0/3a0c_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a0c ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure.,Ding J, Bao J, Zhu D, Zhang Y, Wang DC J Struct Biol. 2010 Sep;171(3):309-17. Epub 2010 May 28. PMID:20546901<ref>PMID:20546901</ref>
Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure.,Ding J, Bao J, Zhu D, Zhang Y, Wang DC J Struct Biol. 2010 Sep;171(3):309-17. Epub 2010 May 28. PMID:20546901<ref>PMID:20546901</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3a0c" style="background-color:#fffaf0;"></div>
==See Also==
*[[Mannose-binding protein|Mannose-binding protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Polygonatum cyrtonema]]
[[Category: Polygonatum cyrtonema]]
[[Category: Ding, J.]]
[[Category: Ding J]]
[[Category: Wang, D C.]]
[[Category: Wang DC]]
[[Category: Beta-prism ii]]
[[Category: Lectin]]
[[Category: Sugar binding protein]]
Retrieved from "https://proteopedia.org/3a0c"