2zkz: Difference between revisions
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==Crystal structure of the transcriptional repressor PagR of Bacillus anthracis== | ==Crystal structure of the transcriptional repressor PagR of Bacillus anthracis== | ||
<StructureSection load='2zkz' size='340' side='right' caption='[[2zkz]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2zkz' size='340' side='right'caption='[[2zkz]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2zkz]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2zkz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZKZ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pagR, tcrA ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pagR, tcrA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zkz OCA], [https://pdbe.org/2zkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zkz RCSB], [https://www.ebi.ac.uk/pdbsum/2zkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zkz ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/PAGR_BACAN PAGR_BACAN]] Represses the expression of the pagA and atxA genes. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/2zkz_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/2zkz_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zkz ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 23: | Line 26: | ||
Crystal structure of the transcriptional repressor PagR of Bacillus anthracis.,Zhao H, Volkov A, Veldore VH, Hoch JA, Varughese KI Microbiology. 2010 Feb;156(Pt 2):385-91. Epub 2009 Nov 19. PMID:19926656<ref>PMID:19926656</ref> | Crystal structure of the transcriptional repressor PagR of Bacillus anthracis.,Zhao H, Volkov A, Veldore VH, Hoch JA, Varughese KI Microbiology. 2010 Feb;156(Pt 2):385-91. Epub 2009 Nov 19. PMID:19926656<ref>PMID:19926656</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2zkz" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Varughese, K I | [[Category: Varughese, K I]] | ||
[[Category: Veldore, V H | [[Category: Veldore, V H]] | ||
[[Category: Volkov, A | [[Category: Volkov, A]] | ||
[[Category: Zhao, H | [[Category: Zhao, H]] | ||
[[Category: Dimer]] | [[Category: Dimer]] | ||
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
Latest revision as of 17:32, 15 December 2021
Crystal structure of the transcriptional repressor PagR of Bacillus anthracis
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