Sandbox Reserved 1: Difference between revisions

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<!-- INSERT YOUR SCENES AND TEXT BELOW THIS LINE -->
<!-- INSERT YOUR SCENES AND TEXT BELOW THIS LINE -->


<Structure load='2YU1' size='350' frame='true' align='right' caption='JmjC domain-containing histone demethylation' scene='2YU1' />


*<scene name='54/545858/2yu1/1'>JmjC domain-containing histone demethylation</scene>
== 4HJE: CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA ==
<Structure load='4hje' size='520' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />
 
<font size="+2">
This protein ('''celluler tumor antigen p53''') is known as a tumor suppressor.
 
So, this protein contact DNA.
 
The regions contacting DNA are
<scene name='54/545858/Scene1/1'>positively charged</scene>.
 
 
<scene name='54/545858/Binding/2'>Lys 120, Arg 248, Arg 280</scene> are important for sequence-specific binding.
 
Lys 120, Arg 280 contact major groove, and Arg 248 contacts minor groove.
 
</font>

Latest revision as of 03:44, 23 May 2015

This Sandbox is Reserved from May 10, 2015, through July 31, 2015 for use by the class Protein 3D Structure Visualization & Structural Bioinformatics taught by Eric Martz and Keiichi Namba at Osaka University, Japan. This reservation includes Sandbox Reserved 1 through Sandbox Reserved 10. Syllabus.
To get started:
  • Click the 'edit this page tab at the top. Save the page after each step, then edit it again.
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4HJE: CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA

Insert caption here

Drag the structure with the mouse to rotate

This protein (celluler tumor antigen p53) is known as a tumor suppressor.

So, this protein contact DNA.

The regions contacting DNA are positively charged.


Lys 120, Arg 248, Arg 280 are important for sequence-specific binding.

Lys 120, Arg 280 contact major groove, and Arg 248 contacts minor groove.

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