Sandbox Reserved 1: Difference between revisions

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<!-- INSERT YOUR SCENES AND TEXT BELOW THIS LINE -->
<!-- INSERT YOUR SCENES AND TEXT BELOW THIS LINE -->


<Structure load='2YU1' size='350' frame='true' align='right' caption='JmjC domain-containing histone demethylation' scene='2YU1' />


JmjC domain-containing histone demethylation
== 4HJE: CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA ==
<Structure load='4hje' size='520' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />


*<scene name='54/545858/2yu1/1'>2YU1</scene>
<font size="+2">
This protein ('''celluler tumor antigen p53''') is known as a tumor suppressor.


Myosin heavy chain, striated muscle
So, this protein contact DNA.


*<scene name='54/545858/1qvi/1'>1QVI</scene>
The regions contacting DNA are
<scene name='54/545858/Scene1/1'>positively charged</scene>.
 
 
<scene name='54/545858/Binding/2'>Lys 120, Arg 248, Arg 280</scene> are important for sequence-specific binding.
 
Lys 120, Arg 280 contact major groove, and Arg 248 contacts minor groove.
 
</font>
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