4jgn: Difference between revisions
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==Crystal structure of RNA silencing suppressor p19 with 1nt-5'-overhanging double-helical RNA 20mer pUUG(CUG)5CU== | ==Crystal structure of RNA silencing suppressor p19 with 1nt-5'-overhanging double-helical RNA 20mer pUUG(CUG)5CU== | ||
<StructureSection load='4jgn' size='340' side='right' caption='[[4jgn]], [[Resolution|resolution]] 1.86Å' scene=''> | <StructureSection load='4jgn' size='340' side='right' caption='[[4jgn]], [[Resolution|resolution]] 1.86Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4jgn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tbsv Tbsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGN FirstGlance]. <br> | <table><tr><td colspan='2'>[[4jgn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tbsv Tbsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JGN FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j39|4j39]], [[1r9f|1r9f]], [[4e5c|4e5c]], [[4e48|4e48]], [[4e6b|4e6b]], [[4j5v|4j5v]], [[4jk0|4jk0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j39|4j39]], [[1r9f|1r9f]], [[4e5c|4e5c]], [[4e48|4e48]], [[4e6b|4e6b]], [[4j5v|4j5v]], [[4jk0|4jk0]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jgn RCSB], [http://www.ebi.ac.uk/pdbsum/4jgn PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgn OCA], [http://pdbe.org/4jgn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jgn RCSB], [http://www.ebi.ac.uk/pdbsum/4jgn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgn ProSAT]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). | |||
==See Also== | |||
*[[P19|P19]] | |||
*[[RNA silencing suppressor|RNA silencing suppressor]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Tbsv]] | [[Category: Tbsv]] | ||
[[Category: Katorcha, E | [[Category: Katorcha, E]] | ||
[[Category: Malinina, L | [[Category: Malinina, L]] | ||
[[Category: Popov, A N | [[Category: Popov, A N]] | ||
[[Category: Tamjar, J | [[Category: Tamjar, J]] | ||
[[Category: Dimer]] | [[Category: Dimer]] | ||
[[Category: Protein-rna complex]] | [[Category: Protein-rna complex]] | ||
Latest revision as of 07:26, 4 August 2016
Crystal structure of RNA silencing suppressor p19 with 1nt-5'-overhanging double-helical RNA 20mer pUUG(CUG)5CU
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