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==Crystal structure of lv-ranaspumin (Lv-RSN-1) from the foam nest of Leptodactylus vastus, orthorhombic crystal form==
==Crystal structure of lv-ranaspumin (Lv-RSN-1) from the foam nest of Leptodactylus vastus, orthorhombic crystal form==
<StructureSection load='4k83' size='340' side='right' caption='[[4k83]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='4k83' size='340' side='right'caption='[[4k83]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k83]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leptodactylus_vastus Leptodactylus vastus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K83 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K83 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k83]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptodactylus_vastus Leptodactylus vastus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K83 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k82|4k82]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k83 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k83 RCSB], [http://www.ebi.ac.uk/pdbsum/4k83 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k83 OCA], [https://pdbe.org/4k83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k83 RCSB], [https://www.ebi.ac.uk/pdbsum/4k83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k83 ProSAT]</span></td></tr>
<table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RANSP_LEPVA RANSP_LEPVA] Acts as a surfactant (PubMed:18689424, PubMed:24442854). Is the major protein constituent (45%) of foam nests (PubMed:27460953). Has no antimicrobial activity, no larvicidal activity, and is not toxic to mice (PubMed:18689424).<ref>PMID:18689424</ref> <ref>PMID:24442854</ref> <ref>PMID:27460953</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Unique crystal structure of a novel surfactant protein from the foam nest of the frog Leptodactylus vastus.,Cavalcante Hissa D, Arruda Bezerra G, Birner-Gruenberger R, Paulino Silva L, Uson I, Gruber K, Maciel Melo VM Chembiochem. 2014 Feb 10;15(3):393-8. doi: 10.1002/cbic.201300726. Epub 2014 Jan , 17. PMID:24442854<ref>PMID:24442854</ref>
Unique crystal structure of a novel surfactant protein from the foam nest of the frog Leptodactylus vastus.,Cavalcante Hissa D, Arruda Bezerra G, Birner-Gruenberger R, Paulino Silva L, Uson I, Gruber K, Maciel Melo VM Chembiochem. 2014 Feb 10;15(3):393-8. doi: 10.1002/cbic.201300726. Epub 2014 Jan , 17. PMID:24442854<ref>PMID:24442854</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4k83" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Leptodactylus vastus]]
[[Category: Leptodactylus vastus]]
[[Category: Bezerra, G A.]]
[[Category: Bezerra GA]]
[[Category: Gruber, K.]]
[[Category: Gruber K]]
[[Category: Hissa, D C.]]
[[Category: Hissa DC]]
[[Category: Melo, V M.M]]
[[Category: Melo VMM]]
[[Category: Alpha-helical]]
[[Category: Amphibian]]
[[Category: Foam nest]]
[[Category: Frog]]
[[Category: Structural protein]]
[[Category: Surfactant protein]]
Retrieved from "https://proteopedia.org/4k83"