3wuz: Difference between revisions
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New page: '''Unreleased structure''' The entry 3wuz is ON HOLD Authors: Kuroki, K., Wang, J., Ose, T., Yamaguchi, M., Tabata, S., Maita, N., Nakamura, S., Kajikawa, M., Kogure, A., Satoh, T., Ara... |
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==Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha== | |||
<StructureSection load='3wuz' size='340' side='right'caption='[[3wuz]], [[Resolution|resolution]] 1.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3wuz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WUZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wuz OCA], [https://pdbe.org/3wuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wuz RCSB], [https://www.ebi.ac.uk/pdbsum/3wuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wuz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PILRA_HUMAN PILRA_HUMAN] Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.<ref>PMID:10903717</ref> <ref>PMID:18358807</ref> <ref>PMID:21241660</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arase H]] | |||
[[Category: Kajikawa M]] | |||
[[Category: Kogure A]] | |||
[[Category: Kuroki K]] | |||
[[Category: Maenaka K]] | |||
[[Category: Maita N]] | |||
[[Category: Nakamura S]] | |||
[[Category: Ose T]] | |||
[[Category: Satoh T]] | |||
[[Category: Tabata S]] | |||
[[Category: Wang J]] | |||
[[Category: Yamaguchi M]] | |||
Latest revision as of 08:47, 20 March 2024
Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha
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