4qc4: Difference between revisions
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New page: '''Unreleased structure''' The entry 4qc4 is ON HOLD Authors: Blaber, M., Xia, X. Description: Crystal structure of C117S mutant of human acidic fibroblast growth factor |
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==Crystal structure of C117S mutant of human acidic fibroblast growth factor== | |||
<StructureSection load='4qc4' size='340' side='right'caption='[[4qc4]], [[Resolution|resolution]] 1.49Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4qc4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QC4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.491Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qc4 OCA], [https://pdbe.org/4qc4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qc4 RCSB], [https://www.ebi.ac.uk/pdbsum/4qc4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qc4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref> | |||
==See Also== | |||
*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Blaber M]] | |||
[[Category: Xia X]] | |||
Latest revision as of 12:45, 1 March 2024
Crystal structure of C117S mutant of human acidic fibroblast growth factor
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