3aqf: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of the human CRLR/RAMP2 extracellular complex==
==Crystal structure of the human CRLR/RAMP2 extracellular complex==
<StructureSection load='3aqf' size='340' side='right' caption='[[3aqf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3aqf' size='340' side='right'caption='[[3aqf]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3aqf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AQF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3aqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AQF FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3aqe|3aqe]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAMP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CALCRL, CGRPR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aqf OCA], [https://pdbe.org/3aqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aqf RCSB], [https://www.ebi.ac.uk/pdbsum/3aqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aqf ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aqf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aqf RCSB], [http://www.ebi.ac.uk/pdbsum/3aqf PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/RAMP2_HUMAN RAMP2_HUMAN] Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.<ref>PMID:22102369</ref> <ref>PMID:9620797</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 14: Line 16:
Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding.,Kusano S, Kukimoto-Niino M, Hino N, Ohsawa N, Okuda K, Sakamoto K, Shirouzu M, Shindo T, Yokoyama S Protein Sci. 2012 Feb;21(2):199-210. doi: 10.1002/pro.2003. Epub 2011 Dec 28. PMID:22102369<ref>PMID:22102369</ref>
Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding.,Kusano S, Kukimoto-Niino M, Hino N, Ohsawa N, Okuda K, Sakamoto K, Shirouzu M, Shindo T, Yokoyama S Protein Sci. 2012 Feb;21(2):199-210. doi: 10.1002/pro.2003. Epub 2011 Dec 28. PMID:22102369<ref>PMID:22102369</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3aqf" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
Line 21: Line 24:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kukimono-Niino, M.]]
[[Category: Large Structures]]
[[Category: Kusano, S.]]
[[Category: Kukimono-Niino M]]
[[Category: Shindo, T.]]
[[Category: Kusano S]]
[[Category: Shirouzu, M.]]
[[Category: Shindo T]]
[[Category: Yokoyama, S.]]
[[Category: Shirouzu M]]
[[Category: Adrenomedullin]]
[[Category: Yokoyama S]]
[[Category: Am-receptor]]
[[Category: Cgrp]]
[[Category: Clr]]
[[Category: Co-activating receptor for adrenomedullin]]
[[Category: Disease]]
[[Category: Endoplasmic reticulum]]
[[Category: Gpcr]]
[[Category: Neovascularization]]
[[Category: Trafficking]]
[[Category: Transmembrane]]
[[Category: Transport protein-membrane protein complex]]
Retrieved from "https://proteopedia.org/3aqf"