4q9m: Difference between revisions
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==Crystal structure of UPPs in complex with FPP and an allosteric inhibitor== | |||
<StructureSection load='4q9m' size='340' side='right'caption='[[4q9m]], [[Resolution|resolution]] 2.06Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4q9m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q9M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2ZW:3-(2-CHLOROPHENYL)-5-METHYL-N-[4-(PROPAN-2-YL)PHENYL]-1,2-OXAZOLE-4-CARBOXAMIDE'>2ZW</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q9m OCA], [https://pdbe.org/4q9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q9m RCSB], [https://www.ebi.ac.uk/pdbsum/4q9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q9m ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ISPT_STRR6 ISPT_STRR6] Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.[HAMAP-Rule:MF_01139] | |||
==See Also== | |||
*[[Inorganic pyrophosphatase 3D structures|Inorganic pyrophosphatase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptococcus pneumoniae R6]] | |||
[[Category: Liu S]] | |||
[[Category: Qiu X]] | |||
Latest revision as of 12:44, 1 March 2024
Crystal structure of UPPs in complex with FPP and an allosteric inhibitor
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